Potkay Biomedical & Microsystems Research Lab

The Potkay Biomedical & Microsystems Research Lab works collaboratively with Michigan Medicine and the VA Ann Arbor Healthcare System to develop artificial lung technologies. Our work applies microfluidic and microsystem approaches to enhance device performance compared to the current state of the art, hollow fiber artificial lung designs. 

Artificial Organs, Microfluidic Artificial Lungs, Bio-MEMS and Microfluidics, Bio-Micro Nanotechnology and Molecular Engineering, Biomedical Computation and Modeling, Biomembranes, Tissue Engineering and Biomaterials, Medical Microsystems, Implantable Sensors, Micro Gas Chromatography Devices and Systems

Fleck, E., Keck, C., Ryszka, K., Zhang, A., Atie, M., Maddox, S. and Potkay, J., 2024. Toward 3D printed microfluidic artificial lungs for respiratory support. Lab on a Chip.

A high-resolution Asiga MAX X27 UV digital light processing (DLP) 3D printer and custom photopolymerizable polydimethylsiloxane (PDMS) resin were used to rapidly manufacture small-scale μALs via vat photopolymerization (VPP). 

This work presents the highest density of 3D printed microchannels in a single device, one of the highest CO2 transfer efficiencies of any artificial lung to date, and a promising approach to translate μALs one step closer to the clinic. 

Dr. Potkay served as guest editor on a special issue of the Micromachines journal on Microfluidic Artificial Organs

Interested in our research? The Potkay Lab is always looking for motivated students to join our team. Contact us!